When you’re frustrated with people, when they’ve made you angry, it just may be because you haven’t given them enough time.
Randy Pausch
Friday, October 30, 2009
Wednesday, October 28, 2009
Like They Are
When you are angry, take no action. When you are fearful, know you are going to exaggerate the dangers you face. War demands the utmost in realism, seeing things as the are.
Robert Greene
Robert Greene
Monday, October 26, 2009
Making Changes
When we are no longer able to change a situation, we are challenged to change ourselves.
Viktor Frankl
Viktor Frankl
Friday, October 23, 2009
Shadows in the Valley
When walking through the valley of shadows, remember, a shadow is cast by a Light.
HK Barclay
HK Barclay
Wednesday, October 21, 2009
Monday, October 19, 2009
Chances and Opportunities
When pessimists think they're taking a chance, optimists feel they're grasping a great opportunity.
Saturday, October 17, 2009
Action Not Talk
When it comes to men that are romantically interested in you, it’s reallysimple. Just ignore everything they say and only pay attention to what they do. - Randy Pausch
Wednesday, October 14, 2009
Life is Hard
"When I hear somebody sigh, 'Life is hard.' I am always tempted to ask. 'Compared to what?'"
The Placebo Gets Stronger
The sugar pill is putting the drug industry in turmoil.
Double-blind study with randomized placebo-controls is the medical gold standard. The FDA won’t put its stamp of approval on a new drug unless the medication has beaten sugar pills in at least two legitimate trials.
But about half of the medications that fail to make it through late-stage trials are losing out to placebos. Even drugs that have been around for years, are failing follow-up tests (one of them is Prozac). Researchers say the problem is not weak medicines but the placebo effect itself. It’s growing stronger.
There’s now a massive effort underway to figure out it’s happening called the Placebo Response Drug Trials Survey.
We already know that the placebo response is related to cultural differences. William Potter of Lilly's neuroscience labs discovered he could predict whether a drug would pass or not based simply on the location of the study. A decade ago, Prozac worked fine in the US but Valium failed. The reverse was true in Europe. The greater the expectation of effectiveness by the patient, the more powerful the placebo’s effect. In countries where volunteers do not have access to the quality of care given during a drug trial, the more likely they are to respond positively to the luxury care coming from American researchers.
Although the most significant ingredient in any placebo is the doctor's bedside manner, even the color of a tablet can boost effectiveness and help to convince a patient that a placebo is really a potent remedy. Doctors have found that calming blue capsules make more effective tranquilizers than fiery red ones.
In each of these cases, the placebo aids recovery by touching the mind's desire and ability to predict the future. We are constantly parsing the reactions of those around to gauge a more accurate estimations of our fate. A doctor’s tone of voice while delivering a diagnosis or the reaction of someone else to the very same medication we ourselves are taking.
Stephen Goforth
Double-blind study with randomized placebo-controls is the medical gold standard. The FDA won’t put its stamp of approval on a new drug unless the medication has beaten sugar pills in at least two legitimate trials.
But about half of the medications that fail to make it through late-stage trials are losing out to placebos. Even drugs that have been around for years, are failing follow-up tests (one of them is Prozac). Researchers say the problem is not weak medicines but the placebo effect itself. It’s growing stronger.
There’s now a massive effort underway to figure out it’s happening called the Placebo Response Drug Trials Survey.
We already know that the placebo response is related to cultural differences. William Potter of Lilly's neuroscience labs discovered he could predict whether a drug would pass or not based simply on the location of the study. A decade ago, Prozac worked fine in the US but Valium failed. The reverse was true in Europe. The greater the expectation of effectiveness by the patient, the more powerful the placebo’s effect. In countries where volunteers do not have access to the quality of care given during a drug trial, the more likely they are to respond positively to the luxury care coming from American researchers.
Although the most significant ingredient in any placebo is the doctor's bedside manner, even the color of a tablet can boost effectiveness and help to convince a patient that a placebo is really a potent remedy. Doctors have found that calming blue capsules make more effective tranquilizers than fiery red ones.
In each of these cases, the placebo aids recovery by touching the mind's desire and ability to predict the future. We are constantly parsing the reactions of those around to gauge a more accurate estimations of our fate. A doctor’s tone of voice while delivering a diagnosis or the reaction of someone else to the very same medication we ourselves are taking.
Stephen Goforth
Monday, October 12, 2009
Friday, October 9, 2009
First Things First
When I have learnt to love God better than my earthly dearest, I shall love my earthly dearest better than I do now.... When first things are put first, second things are not suppressed but increased.
C.S. Lewis
C.S. Lewis
Wednesday, October 7, 2009
What You Become
What you get by achieving your goals is not as important as what you become by achieving your goals.
Zig Ziglar
Zig Ziglar
Monday, October 5, 2009
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